For the identification of cellular targets, Formalin-fixed Paraffin-embedded Tissue Blocks (FFPE) can be used to identify normal and diseased tissue. All our tissues have been fixed in 10% formalin, and then carefully embedded in IHC grade paraffin.
Paraffin embedding can be used in research and clinical laboratories to create formalin-fixed, paraffin-embedded tissue blocks. To create a paraffin block, or FFPE block, the tissue that has been formin-fixed undergoes tissue processing. You can use a microtome or a knife to cut the paraffin block. This allows you to create thin sections of paraffin tissue that can be stained or made into paraffin tissue ribbons for nucleic acids extraction. However, you can go to the search engines to know several FFPE segment repositories methods.
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The FFPE blocks can also be kept at room temperature for many years. These are just a few of the benefits of FFPE tissue blocks. Let's have a look at the upcoming paragraphs to know about them.
If FFPE blocks were used, it is possible to complete the entire cohort of studies in one experiment. Large cohorts also produce rapid results.
TMA requires only 1ml of total reagent volume to perform the entire cohort.
TMA does not require differential antigen retrieval
TMAs can be stained with a variety of methods, including in situ hybridization, chromogenic and fluorescent visualization, tissue microdissection, or other non-conventional FFPE.
FFPE blocks can easily be cored multiple times without destroying them.
It has been proven that FFPE blocks can last for over 60 years. This makes it applicable to the study of archival tissue.